Encyclopedia of Cancer

The chapter on mevalonate pathway, which I authored together with my colleague Franz Varga has appeared in the recent edition of The Encyclopedia of Cancer (3rd edition, vol.2, Elsevier Academic Press, pp. 445-457). Downloads (see: publications>epigenetic) are allowed for non-commercial research and educational use. 

Lecture Epigenetic Conference 2017

Here is the lecture on "Epigenetic aspects of antineoplastic activities from drugs affecting mevalonate metabolism" for the Epigenetics conference in Frankfurt on Nov. 6th, 2017.

Lecture 2017

This is my actual presentation on epigenetics.

Statins and Bisphosphonates against cancer

Our new publication which shows how statins and bisphosphonates induce a process of starvation in fast growing cancer cells has been published in the IJMS (International Journal of Molecular Science).

LBG Health Meeting 2016

Here are our Posters, which have been presented at the Health Meeting from the Ludwig Boltzmann Society in Vienna on November 28th and 29th 2016.

Interaction of bone and leukemic cells

An article discussing the cose interaction from bone and leukemic cells is published in the journal JATROS.

Leukemia and Bone Cells

This poster was presented at the spring meeting of the Austrian Society for Hematology and Oncology (Mar 17-19, 2016).

Epigenetic effect of Simvastatin in neoplastic mast cells

This poster was presented on the 20th Congress of the European Hematology Association in Vienna (June 11-14, 2015).

Epigenetics of Mevalonate Metabolism

This article provides some insight into the epigenetic mechanisms, which may be responsible  for the anti-cancer activities of statins and bisphosphonates

Epigenetics of Mevalonate Metabolism Poster

This poster is presented at the spring meeting of the Austrian Society for Hematology and Oncology (April 24th 2015). It focuses on different effects of statins and bisphosphonates on respective gene expression patterns.

Epigenetics of Vitamin D Metabolism

This poster, which is presented at the Epigenetic control of hematopoiesis and leukemogenesis Symposium in Strasbourg on April 21st 2015, illustrates the epigenetic activity of vitamin D.

Epigenetics and the Power of Art

Here is one of the first publications indicating the connection between epigenetics and artistic performance.

The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia

VO Stress, Gender Epigenetik

Vorlesung Stress, Gender Epigenetik

Impact of Vitamin D Metabolism on Clinical Epigenetics

The beneficial effects of vitamin D for prevention and treatment of numerous diseases are well known. This publication gives interesting insights on the molecular background of vitamin D-action.

Epigenetic effect of homocysteine

Our great study demonstrating how the type-2 diabetes - associated metabolite homocysteine may exert its cancerogeneic potential is now published in the "Journal of Biological Chemistry".

Epigenetics and Human Health Book Chapter Text

Effects of Epigenetic Drugs (Vorinostat, Decitabine) on Metabolism- Related Pathway Factors in Leukemic Cells

This article demonstrates the inhibitory effect of epigenetically active drugs on energy metabolism of leukemia cell lines. Suppementary Figures available on request.

Epigenetik Überraschend starke Einflüsse von Ernährung, Lifestyle und Umwelt auf das Genom und seine Vererbung

Epigenetics and Human Health: Linking Hereditary, Environmental and Nutritional Aspects

Extra-celluar matrix suppresses expression of the apoptosis mediator Fas by epigenetic DNA methylation

Epigenetic regulation of human buccal mucosa mitochondrial superoxide dismutase gene expression by diet